Herbal Viagra actually contains the real thing



































IF IT looks too good to be true, it probably is. Several "herbal remedies" for erectile dysfunction sold online actually contain the active ingredient from Viagra.












Michael Lamb at Arcadia University in Glenside, Pennsylvania, and colleagues purchased 10 popular "natural" uplifting remedies on the internet and tested them for the presence of sildenafil, the active ingredient in Viagra. They found the compound, or a similar synthetic drug, in seven of the 10 products – cause for concern because it can be dangerous for people with some medical conditions.












Lamb's work was presented last week at the American Academy of Forensic Sciences meeting in Washington DC.












This article appeared in print under the headline "Herbal Viagra gets a synthetic boost"


















































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One dead, dozens hurt in Egypt Nile Delta clashes






CAIRO: One person was killed and dozens injured in overnight clashes between police and protesters in Egypt's Nile Delta city of Mansura, a security official told AFP on Saturday.

A week of demonstrations in Mansura turned violent late on Friday when police fired tear gas at protesters outside the governorate headquarters, witnesses said.

"One protester died while 30 protesters and 10 policemen were injured in the clashes," the security official said.

According to media reports, the protester died after he was run over by a police van.

The security official said protesters had tried to storm the government building, prompting the police to fire tear gas.

Egypt has been gripped by nationwide unrest in recent months, with protesters taking to the streets to denounce Islamist President Mohamed Morsi for failing to address political and economic concerns.

Mansura is the latest province to launch a campaign of civil disobedience, following in the footsteps of the canal cities of Port Said, Ismailiya and Suez.

Opponents accuse Morsi of failing the revolution that brought him to the presidency and of consolidating power in the hands of his Muslim Brotherhood.

- AFP/xq



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Chinatown landmark named for pioneering jurist









He was the first Chinese American graduate of Stanford Law School and the first Chinese American judge to be appointed to the bench in the continental United States.


On Friday, he became the first Chinese American to have a Los Angeles landmark named after him: Judge Delbert E. Wong Square, which encompasses the intersection of Hill and Ord streets at the western edge of Chinatown.


Councilman Ed Reyes hopes that someday the stretch of Hill Street that runs in front of the Chinatown public library will be named after Wong, who died in 2006 at age 85. Wong and his wife, Dolores, were instrumental in getting the library built, so the location would be fitting.





"The square is a starting point," said Reyes, who presided over the dedication.


A street in Little Tokyo bears the name of Judge John Aiso, the nation's first Japanese American judge.


Wong was born in the Central Valley town of Hanford in 1920, the son of a grocer from China's Guangdong province. The family later moved to Bakersfield, where Chinese and other minorities were restricted to the balconies of movie theaters and could only use the public swimming pool on Fridays, according to an oral history by Wong's son, Marshall Wong.


Wong graduated from UC Berkeley and enlisted in the Army Air Forces during World War II. As a navigator on a B-17 Flying Fortress, he completed 30 bombing missions in Europe, earning a Distinguished Flying Cross and four Air Medals.


When he returned home, Wong decided to attend law school. His parents disapproved, fearing that racial prejudice would prevent him from finding work.


After graduating from Stanford, Wong found that his job options were indeed limited. The few Chinese American attorneys in California practiced immigration law. Wong gravitated to the public sector, working as a deputy legislative counsel and then as a deputy state attorney general.


In 1959, Wong became the first Chinese American judge in the continental United States when then-Gov. Pat Brown appointed him to the Los Angeles County Municipal Court. He later joined the Superior Court, serving for more than two decades. He continued to make headlines in retirement, leading a probe into racial discrimination at the Los Angeles Airport Police Bureau and working as a special master in the O.J. Simpson case.


Wong and his wife were among the founding benefactors of the Asian Pacific American Legal Center and the Chinatown Service Center. They were also pioneers in another arena: housing. After a real estate agent told them that Chinese could not buy in Silver Lake, they sought out the property's owner, who was happy to sell to them.


Wong's widow and three of his four children attended Friday's dedication.


California now has more than 90 Asian American trial judges. Four of seven state Supreme Court justices are Asian American, including Chief Justice Tani Cantil-Sakauye. But young people passing through Judge Delbert E. Wong Square should remember those who paved the way, perhaps even drawing inspiration from them, Marshall Wong said.


"The children who grow up in this neighborhood will pass by and wonder, 'Who was Judge Wong?' Hopefully, they'll learn something about his story and his work and think, 'Maybe I should go to law school and be a judge someday.'"


cindy.chang@latimes.com





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Black Hole Spins at Nearly the Speed of Light


A superfast black hole nearly 60 million light-years away appears to be pushing the ultimate speed limit of the universe, a new study says.

For the first time, astronomers have managed to measure the rate of spin of a supermassive black hole—and it's been clocked at 84 percent of the speed of light, or the maximum allowed by the law of physics.

"The most exciting part of this finding is the ability to test the theory of general relativity in such an extreme regime, where the gravitational field is huge, and the properties of space-time around it are completely different from the standard Newtonian case," said lead author Guido Risaliti, of the Harvard-Smithsonian Center for Astrophysics (CfA) and INAF-Arcetri Observatory in Italy. (Related: "Speedy Star Found Near Black Hole May Test Einstein Theory.")

Notorious for ripping apart and swallowing stars, supermassive black holes live at the center of most galaxies, including our own Milky Way. (See black hole pictures.)

They can pack the gravitational punch of many million or even billions of suns—distorting space-time in the region around them, not even letting light to escape their clutches.

Galactic Monster

The predatory monster that lurks at the core of the relatively nearby spiral galaxy NGC 1365 is estimated to weigh in at about two million times the mass of the sun, and stretches some 2 million miles (3.2 million kilometers) across-more than eight times the distance between Earth and the moon, Risaliti said. (Also see "Black Hole Blast Biggest Ever Recorded.")

Risaliti and colleagues' unprecedented discovery was made possible thanks to the combined observations from NASA's high-energy x-ray detectors on its Nuclear Spectroscopic Telescope Array (NuSTAR) probe and the European Space Agency's low-energy, x-ray-detecting XMM-Newton space observatory.

Astronomers detected x-ray particle remnants of stars circling in a pancake-shaped accretion disk surrounding the black hole, and used this data to help determine its rate of spin.

By getting a fix on this spin speed, astronomers now hope to better understand what happens inside giant black holes as they gravitationally warp space-time around themselves.

Even more intriguing to the research team is that this discovery will shed clues to black hole's past, and the evolution of its surrounding galaxy.

Tracking the Universe's Evolution

Supermassive black holes have a large impact in the evolution of their host galaxy, where a self-regulating process occurs between the two structures.

"When more stars are formed, they throw gas into the black hole, increasing its mass, but the radiation produced by this accretion warms up the gas in the galaxy, preventing more star formation," said Risaliti.

"So the two events—black hole accretion and formation of new stars—interact with each other."

Knowing how fast black holes spin may also help shed light how the entire universe evolved. (Learn more about the origin of the universe.)

"With a knowledge of the average spin of galaxies at different ages of the universe," Risaliti said, "we could track their evolution much more precisely than we can do today."


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Venezuela rejects "absurd" rumors over Chavez's death


CARACAS (Reuters) - Senior aides and relatives of Venezuela's Hugo Chavez countered on Friday a crescendo of rumors that the socialist president may be dead from cancer, saying he was still battling for his life.


"There he is, continuing his fight, his battle, and we are sure of victory!" his older brother Adan Chavez, the governor of Barinas state, told cheering supporters.


Speculation about Chavez, 58, hit fever pitch this week, fed in part by assertions from Panama's former ambassador to the Organization of American States (OAS), Guillermo Cochez, that the Venezuelan leader had died.


"The launching of absurd and bizarre rumors by the right wing simply discredits them and isolates them further from the people," said Chavez's son-in-law Jorge Arreaza, adding that the president was "calm" in a hospital with his family and doctors.


Apart from one set of photos showing Chavez lying in a Havana hospital bed, he has not been seen nor heard from in public since December 11 surgery in Cuba, his fourth operation.


The president made a surprise pre-dawn return to a military hospital in Caracas last week, with none of the fanfare that had accompanied his previous homecomings after treatment.


Vice President Nicolas Maduro, the OPEC nation's de facto leader and Chavez's preferred successor, urged Venezuelans to stay calm, patient and respectful of the president's state.


"The treatments Commander Chavez is receiving are tough, but he is stronger than them," Maduro said after a Catholic Mass in Chavez's honor at a chapel in the hospital.


"He's in good spirits, battling ... . Leave him in peace. He deserves respect for his treatments, because he's a man who has given everything for our fatherland."


Opposition politicians accuse the government of being deceitful about Chavez's condition, and compare the secrecy over his medical details with the transparency shown by other Latin American leaders who have suffered cancer.


"Maduro has lied repeatedly to the president's supporters and to Venezuelans about his real situation," opposition leader Henrique Capriles said on Friday. "Let's see how they explain to the nation in coming days all the lies they have told."


Panamanian diplomat Cochez said Chavez's relatives had switched off his life support several days ago after he had been in a vegetative state since the end of December. He challenged officials to prove him wrong by showing the president in public.


HIGH STAKES


Across the South American nation of 29 million people, Venezuelans are extremely anxious, speculating almost non-stop about Chavez's condition and wondering what the potential end of his 14-year rule might mean for them.


Adding to the tension, several dozen opposition-supporting students have chained themselves together in a Caracas street, demanding to see the president and arguing that Maduro has no right to rule because he was not elected.


With the country on edge, the relatively routine shooting by police of a murder suspect during a gun battle in downtown Caracas on Friday forced Information Minister Ernesto Villegas to take to Twitter to issue reassurances.


"(Some people) took advantage of the episode to try to sow panic in the city center," he said. "The situation is calm."


Should Chavez die or step down, a vote would be held within 30 days, probably pitting Maduro against Capriles for leadership of the country which boasts the world's biggest oil reserves.


The stakes are high for the region, too. Chavez has been the most vocal critic of Washington in Latin America and financed hefty aid programs for leftist governments from Cuba to Bolivia.


Amid the flurry of rumors, Spain's ABC newspaper said on Friday that Chavez had been taken to a presidential retreat on La Orchila island in the Caribbean off Venezuela's coast with his closest family to face the "final stages" of his cancer.


Venezuelan officials have frequently lambasted ABC as being part of an "ultra-right" conspiracy spreading lies about Chavez.


"The bourgeoisie harass him and they assault him constantly," added Maduro, singling out ABC and Colombia's Caracol radio for particular criticism.


"Stop the attacks on the commander! Stop the rumors, stop trying to create instability!"


In the latest of a series of short updates on Chavez's health, the government said last week that his breathing difficulties had worsened, and he was using a tracheal tube.


Officials say he suffered a severe respiratory infection following the six-hour operation he had in December for a cancer that was first detected in his pelvic region in June 2011.


Chavez has never said what type of cancer he has.


Remarkably, two opinion polls this week showed that a majority of Venezuelans - 60 percent in one survey, 57 percent in another - believe he will be cured.


Chavez's millions of passionate supporters, who love his down-to-earth style and heavy spending of oil revenue on welfare policies, are struggling to imagine Venezuela without him.


"Of course, he's coming back, back to government," said Jose Urbina, 47, though he was also buying photos of Chavez at a pro-government rally as mementoes. "I want to remember him. I want to put them in my house."


(Additional reporting by Girish Gupta; Editing by Kieran Murray and Xavier Briand)



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Space gold rush should not be a free-for-all






















We need a consensus on regulations surrounding space mining if it’s to enrich us all
















EVER since we took our first steps out of Africa, human exploration has been driven by the desire to secure resources. Now our attention is turning to space.












The motivation for deep-space travel is shifting from discovery to economics. The past year has seen a flurry of proposals aimed at bringing celestial riches down to Earth. No doubt this will make a few billionaires even wealthier, but we all stand to gain: the mineral bounty and spin-off technologies could enrich us all.












But before the miners start firing up their rockets, we should pause for thought. At first glance, space mining seems to sidestep most environmental concerns: there is (probably!) no life on asteroids, and thus no habitats to trash. But its consequences – both here on Earth and in space – merit careful consideration.












Part of this is about principles. Some will argue that space's "magnificent desolation" is not ours to despoil, just as they argue that our own planet's poles should remain pristine. Others will suggest that glutting ourselves on space's riches is not an acceptable alternative to developing more sustainable ways of earthly life.












History suggests that those will be hard lines to hold, and it may be difficult to persuade the public that such barren environments are worth preserving. After all, they exist in vast abundance, and even fewer people will experience them than have walked through Antarctica's icy landscapes.











There's also the emerging off-world economy to consider. The resources that are valuable in orbit and beyond may be very different to those we prize on Earth (see "Space miners hope to build first off-Earth economy"). Questions of their stewardship have barely been broached – and the relevant legal and regulatory framework is fragmentary, to put it mildly.













Space miners, like their earthly counterparts, are often reluctant to engage with such questions. One speaker at last week's space-mining forum in Sydney, Australia, concluded with a plea that regulation should be avoided. But miners have much to gain from a broad agreement on the for-profit exploitation of space. Without consensus, claims will be disputed, investments risky, and the gains made insecure. It is in all of our long-term interests to seek one out.


















This article appeared in print under the headline "Taming the final frontier"


















































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Football: Giggs signs new one-year deal at Man Utd - club






LONDON: Ryan Giggs, who is set to make his 1,000th appearance in senior football this weekend, has signed a new one-year contract at Manchester United, the club announced on Friday.

The English Premier League leaders said the deal keeps the 39-year-old Wales winger at Old Trafford until June 2014 and sees him complete a 23rd season as a first-team player.

Coach Alex Ferguson told manutd.com: "What can I say about Ryan that hasn't already been said? He is a marvellous player and an exceptional human being. Ryan is an example to us all, the way in which he has, and continues to, look after himself.

"He has fantastic energy for the game and it is wonderful to see. Ryan seems to reach a new milestone every week and to think that he now has 23 unbroken years of league goals behind him is truly amazing in the modern-day game.

"His form this year shows his ability and his enjoyment of the game are as strong as ever and I am absolutely delighted that he has signed a new contract."

Giggs signed professional forms with United in 1990 and made his debut on March 2, 1991.

He has made 931 appearances for the club -- a Manchester United record -- and scored 168 goals.

He has been capped 64 times for Wales and played four times for the British Olympic men's football team at last year's London Games.

During his impressive storied career, he has won 12 Premier League titles, four FA Cups, three League Cups, two Champions Leagues, one Super Cup, an Intercontinental Cup and a FIFA Club World Cup.

Giggs said he was "delighted" to have signed a new contract and despite his advancing years said he was "feeling good, enjoying my football more than ever and, most importantly, I feel I am making a contribution to the team".

He added: "This is an exciting team to be part of, with great team spirit, and we are again pushing for trophies as we head towards the business end of the season."

-AFP/sb



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Las Vegas Strip shooting suspect is arrested in L.A.









A man suspected in a deadly car-to-car shooting in the heart of the Las Vegas Strip was arrested Thursday at a Studio City apartment complex, bringing an end to a weeklong manhunt.


Los Angeles police and FBI agents surrounded the suburban apartment complex in the 4100 block of Arch Drive about noon and ordered Ammar Harris to surrender. Officers said there was a woman inside the apartment where he was holed up; she was not arrested.


Harris, 26, is being held on suspicion of murder and is expected to be extradited back to Nevada.





"This arrest is much more than just taking Ammar Harris," said Las Vegas Sheriff Doug Gillespie, speaking at police headquarters near the Strip. "The citizens of our community as well as tourists who visit and work in the Las Vegas Valley are entitled to a safe community."


Harris — described by law enforcement officials as a man with an "extensive and violent criminal history" — is accused of being the gunman in the Feb. 21 shooting that killed three people, including Kenneth Cherry Jr., an Oakland native and rapper known as Kenny Clutch.


Las Vegas police said Harris opened fire from his Ranger Rover on Cherry's Maserati on Las Vegas Boulevard after an altercation at a valet stand at the Aria hotel resort.


The Maserati then sped into the intersection at Flamingo Road, where it rammed a Yellow Cab, which erupted in flames near the mega-wattage casinos of the Bellagio, the Flamingo and Ceasars Palace. The explosion killed the taxi driver and passenger inside.


Cherry and a passenger in his Maserati were taken to a hospital, where Cherry was pronounced dead. Four other vehicles were involved in the fiery crash, which left three other people with injuries.


"What I can tell you is that Mr. Harris' behavior was unlike any other I've seen, and I've been in this community in law enforcement for 32 years," Clark County Dist. Atty. Steve Wolfson said.


"I cannot imagine anything more serious than firing a weapon from a moving vehicle into another moving vehicle on a corner such as Las Vegas Boulevard and Flamingo."


Even in a city accustomed to spectacle, the shooting and collision were shocking.


On the night of the shooting, Harris was accompanied by three people in his Range Rover, none considered suspects, said Lt. Ray Steiber of the Las Vegas Metropolitan Police Department. On Saturday, Las Vegas police found Harris' black Range Rover at an apartment complex in the city. The district attorney charged Harris with murder even though he could not be located, and a federal magistrate signed off on a charge of fleeing the jurisdiction.


Federal court documents show Las Vegas homicide detectives suspected that Harris may have fled to California because his phone showed he made calls in the state.


According to law enforcement sources, Harris operated as a pimp in Las Vegas. In a video released by Las Vegas police, Harris flashed a fistful of $100 bills as he bragged about the money. He boasted about money, guns, expensive cars and run-ins with the law on social media accounts, authorities said.


On one social media site, using the name Jai'duh, someone authorities believe was Harris posted pictures of stacks of $100 bills and a Carbon 15 pistol.


Harris' record includes a 2010 arrest in Las Vegas on suspicion of pimping-related offenses of pandering with force and sexual assault. He has previously been arrested on suspicion of a variety of crimes in South Carolina and Georgia, authorities said.


Harris is slated to appear in a downtown Los Angeles courtroom Monday for an extradition proceeding.


richard.winton@latimes.com


john.glionna@latimes.com


kate.mather@latimes.com


Glionna reported from Las Vegas. Times staff writer Andrew Blankstein contributed to this report.





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Scarred Duckbill Dinosaur Escaped T. Rex Attack


A scar on the face of a duckbill dinosaur received after a close encounter with a Tyrannosaurus rex is the first clear case of a healed dinosaur wound, scientists say.

The finding, detailed in the current issue of the journal Cretaceous Research, also reveals that the healing properties of dinosaur skin were likely very similar to that of modern reptiles.

The lucky dinosaur was an adult Edmontosaurus annectens, a species of duckbill dinosaur that lived in what is today the Hell Creek region of South Dakota about 65 to 67 million years ago. (Explore a prehistoric time line.)

A teardrop-shaped patch of fossilized skin about 5 by 5 inches (12 by 14 centimeters) that was discovered with the creature's bones and is thought to have come from above its right eye, includes an oval-shaped section that is incongruous with the surrounding skin. (Related: "'Dinosaur Mummy' Found; Have Intact Skin, Tissue.")

Bruce Rothschild, a professor of medicine at the University of Kansas and Northeast Ohio Medical University, said the first time he laid eyes on it, it was "quite clear" to him that he was looking at an old wound.

"That was unequivocal," said Rothschild, who is a co-author of the new study.

A Terrible Attacker

The skull of the scarred Edmontosaurus also showed signs of trauma, and from the size and shape of the marks on the bone, Rothschild and fellow co-author Robert DePalma, a paleontologist at the Palm Beach Museum of Natural History in Florida, speculate the creature was attacked by a T. rex.

It's likely, though still unproven, that both the skin wound and the skull injury were sustained during the same attack, the scientists say. The wound "was large enough to have been a claw or a tooth," Rothschild said.

Rothschild and DePalma also compared the dinosaur wound to healed wounds on modern reptiles, including iguanas, and found the scar patterns to be nearly identical.

It isn't surprising that the wounds would be similar, said paleontologist David Burnham of the University of Kansas Biodiversity Institute, since dinosaurs and lizards are distant cousins.

"That's kind of what we would expect," said Burnham, who was not involved in the study. "It's what makes evolution work—that we can depend on this."

Dog-Eat-Dog

Phil Bell, a paleontologist with the Pipestone Creek Dinosaur Initiative in Canada who also was not involved in the research, called the Edmontosaurus fossil "a really nicely preserved animal with a very obvious scar."

He's not convinced, however, that it was caused by a predator attack. The size of the scar is relatively small, Bell said, and would also be consistent with the skin being pierced in some other accident such as a fall.

"But certainly the marks that you see on the skull, those are [more consistent] with Tyrannosaur-bitten bones," he added.

Prior to the discovery, scientists knew of one other case of a dinosaur wound. But in that instance, it was an unhealed wound that scientists think was inflicted by scavengers after the creature was already dead.

It's very likely that this particular Edmontosaurus wasn't the only dinosaur to sport scars, whether from battle wounds or accidents, Bell added.

"I would imagine just about every dinosaur walking around had similar scars," he said. (Read about "Extreme Dinosaurs" in National Geographic magazine.)

"Tigers and lions have scarred noses, and great white sharks have got dings on their noses and nips taken out of their fins. It's a dog-eat-dog world out there, and [Edmontosaurus was] unfortunately in the line of fire from some pretty big and nasty predators ... This one was just lucky to get away."

Mysterious Escape

Just how Edmontosaurus survived a T. rex attack is still unclear. "Escape from a T. rex is something that we wouldn't think would happen," Burnham said.

Duckbill dinosaurs, also known as Hadrosaurs, were not without defenses. Edmontosaurus, for example, grew up to 30 feet (9 meters) in length, and could swipe its hefty tail or kick its legs to fell predators.

Furthermore, they were fast. "Hadrosaurs like Edmontosaurus had very powerful [running] muscles, which would have made them difficult to catch once they'd taken flight," Bell said.

Duckbills were also herd animals, so maybe this one escaped with help from neighbors. Or perhaps the T. rex that attacked it was young. "There's something surrounding this case that we don't know yet," Burnham said.

Figuring out the details of the story is part of what makes paleontology exciting, he added. "We construct past lives. We can go back into a day in the life of this animal and talk about an attack and [about] it getting away. That's pretty cool."


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Bacteria defeat antibiotics they have never met before



































BACTERIA that resist antibiotics are a growing problem worldwide, but one we thought we could limit or even reverse by better control of the drugs. This may be a forlorn hope: some bacteria that have never seen an antibiotic can evolve resistance, and even thrive on it.











Bacteria usually become resistant if they are exposed to drug levels too low to kill them off, but high enough to favour the survival of resistant mutants. Such resistance is growing and could make TB and other diseases untreatable again.













The prevailing notion was that bacteria acquire and maintain resistance genes at a cost. So by carefully controlling antibiotics, resistance should not emerge by itself – and should die out as soon as the antibiotic is withdrawn and resistance is no longer an advantage.












Maybe not. Olivier Tenaillon at Denis Diderot University, Paris, and colleagues were studying bacterial evolution by exposing Escherichia coli to high temperatures and little food. Unexpectedly, some bacteria spontaneously became resistant to the antibiotic rifampicin, even though they had never encountered it. The mutation that helped them deal with environmental stress just happened to confer resistance to the drug, used to treat TB and meningitis (BMC Evolutionary Biology, doi.org/kks).


















"Our work suggests that selective pressure other than antibiotics may drive resistance," says Tenaillon.












Moreover, bacteria with the mutation grew 20 per cent faster than otherwise-identical bacteria – a first for a resistance mutation.












It only had this beneficial effect in the heat-adapted strain, says Arjan de Visser of Wageningen University in the Netherlands, who was not involved in the study. But, he adds, "these results are a cautionary tale for the use of antibiotics – resistance may come without costs [to bacteria]".












This article appeared in print under the headline "Bacteria defeat antibiotics they have never met"




















































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